IFNG and breast cancer: To determine whether Ifng is a critical factor in breast cancer eradication by SRC-3 KO Tregs, breast tumor–bearing SRC-3f/f and SRC-3d/d:Treg female mice were intraperitoneally injected with anti-Ifng antibody and rat IgG as the control IgG (SI Appendix, Fig. S11A).