Interestingly, it has recently been shown that the polyglycine region of FMRpolyG (the toxic protein generated from repeat-associated non-AUG translation of FMR1, a posited contributor to neurotoxicity in FXTAS) has a prion-like domain with low complexity similar to the so-called prion proteins in yeast, and that it may propagate cell to cell in a prion-like manner (70). This evidence concerns the gene FMR1 and fragile X-associated tremor/ataxia syndrome.