Accordingly, as shown in Table 4 below those bi-variable regression associated with the crude odds ratios (COR) treatment outcome of neonatal sepsis such as education status of the mothers, place of delivery, gestational age < 37weeks, birth weight of the neonate, age of the neonate admitted to NICU, sever chest in drawing, grunting, un able to feed, temperature, Chorioamnaties, meconium amniotic stained, PROM, Hypertensive PIH/ Eclampsia, meropenum, vancomycin, metronidazole, CBC and CRP result. Here, CRP is linked to Neonatal sepsis.