For example, results of ongoing clinical trials, including those evaluating the incidence of arrhythmic events before and after SGLT2 inhibitor treatment in patients with type 2 diabetes mellitus with ICD (85) and in patients with heart failure with ICD (86), may provide a major clue for revealing the association between the use of SGLT2 inhibitors and the incidence of SCD as well as VAs. This evidence concerns the gene SLC5A2 and Schnyder corneal dystrophy.