For example, results of ongoing clinical trials, including those evaluating the incidence of arrhythmic events before and after SGLT2 inhibitor treatment in patients with type 2 diabetes mellitus with ICD (85) and in patients with heart failure with ICD (86), may provide a major clue for revealing the association between the use of SGLT2 inhibitors and the incidence of SCD as well as VAs. The gene discussed is SLC5A2; the disease is type 2 diabetes mellitus.