AKT1 and familial pancreatic carcinoma: The pathways enriched in the high-risk group were mainly associated with pancreatic cancer, apoptosis, mismatch repair, cell cycle, spliceosome, hypoxia, glycolysis, P53 signaling, MYC signaling, TGF-beta signaling, and PI3K/Akt signaling (Figures 9A, B).