screened potential autoantibody-based markers for hepatocellular carcinoma (HCC) and found that the AUC of an immunodiagnostic model including 6 TAAbs (RAD23A, CAST, RUNX1T1, PAIP1, SARS, PRKCZ) were 0.835 and 0.788 in the training and validation sets, respectively (27). This evidence concerns the gene CAST and hepatocellular carcinoma.