The role of LDLRAD3 in cancer has not been extensively studied, however, LDLRAD3 is overexpressed in several types of cancers including breast cancer, glioma, prostate adenocarcinoma, skin cutaneous melanoma, testicular germ cell tumor, and pancreatic cancer (TCGA, data not shown). The gene discussed is LDLRAD3; the disease is familial pancreatic carcinoma.