ALK and cancer: This model was based on the mRMR FS method and the ANN classifier, trained with 32 features addressing the following clinical variables: socioeconomic level, primary symptom, previous dyspnea, pleuritic pain, outcomes of PET and pulmonary function tests, tumor characteristics (location and TNM), ALK expression, family cancer history, QoL, and RT dose at heart, CTV, and GTV.