AKR1C1 and gastric adenocarcinoma: We utilized the “edgR” package to conduct a differential analysis of 18 ferroptosis-related genes with significant differential expression in gastric adenocarcinoma, resulting in 12 upregulated genes (ALB, ALOX15, GDF15, CDKN2A, HELLS, MIOX, TRIB3, AURKA, NOX1, CP, NOS2, and MYB) and 6 downregulated genes (ANGPTL7, PLIN4, ALOX12, TP63, HBA1, and AKR1C1) (Figures 2(a) and 2(b)).