The prognostic model proposed in the present study was composed of 11 estrogen response-related genes (AGR2, CA12, ELF3, ESRP2, FGFR3, KLK10, KLK11, PKP3, SFN, SCNN1A, TRIM29), among which many genes correlated with tumor immunity and immunotherapy. The gene discussed is SFN; the disease is neoplasm.