cDC2s are crucial for the induction of CD4+ T helper cell 2 (Th2) responses (12, 14, 15), while cDCs1 have superior cross-presenting potential and induce cytotoxic T cells against virus-infected cells or tumor cells and are therefore explored as tools for anti-virus or anti-tumor vaccination strategies (16–21). The gene discussed is CD4; the disease is neoplasm.