Although that study did not show increased STAT6 expression, it is known that STAT6 signaling is affected in asthma and, together with elevated levels of IL-4 and IL-13 driven by Th2 immune responses, leads to mucus hypersecretion in mice, which is a characteristic for asthma, COPD, and CF (148). The gene discussed is STAT6; the disease is cystic fibrosis.