IFNB1 and polyarticular juvenile idiopathic arthritis: History aside, we also appreciate how, despite the difficulty of being a woman scientist in a field mostly dominated by men, she contributed so much to blockbuster biological drugs such as Rebif (IFN-β) for multiple sclerosis and etanercept for rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, polyarticular juvenile arthritis and ankylosing spondylitis.