In addition, IRF7 can upregulate the expression of anti-inflammatory genes such as IL10 and downregulate pro-inflammatory genes such as IL1B, TNF, CXCL1 and CXCL2 to polarize microglia to the M2 type, thereby establishing a tumor microenvironment that exerts immunosuppressive effects. This evidence concerns the gene IRF7 and neoplasm.