In the cancer context, a study found that there is no difference at the level of phosphorylated ribosomal protein S6 regulating signaling pathways, including PI3K/AKT/mTOR and RAS-ERK between control T cells and SLAMF6-/- T cells (114), suggesting SLAMF6 might be associated with these signaling pathways. The gene discussed is SLAMF6; the disease is cancer.