CD4 and cancer: Cancer cell antigen release (step 1), CD4 T cells, CDB T cells, macrophages, and other cell recruitment (step 4), T-cell-to-tumor cell recognition (step 6), tumor cell clearance (step 7), etc. Further analysis of the composition of immune-infiltrating cells in the tumor microenvironment of senescence subtypes of TNBC showed that the TNBCSASP1 subtype had a lower infiltration of DCs than the TNBCSASP2 subtype (Figure 7E).