The findings of the study demonstrated that BCP reduced obesity-related AHR by inhibiting macrophage polarisation, activating AMPK, activating Nrf2/HO-1, increasing AdipoR1 and AdipoR2 expression, and decreasing NFB expression in the lungs of animals (Pathak et al., 2021). This evidence concerns the gene HMOX1 and obesity due to melanocortin 4 receptor deficiency.