Likewise, stamen extract of Mesua ferrea L. (Calophyllaceae) from the Calophyllaceae family and root extract of Clerodendrum serratum of the genus Clerodendrum is reported to ameliorate allergic asthma through the modulation of few asthma-associated cytokines like TNF-α, IL-5, and IL-4. The gene discussed is IL5; the disease is asthma.