According to univariate analysis, age, MELD score, PLT, INR, levels of ALT, AST, TBIL, ALB, γ-GGT, and Cr, AFP ≥400 ng/mL, tumor size ≥5 cm, multiple tumors, and BCLC C–D stages were risk factors for mortality before PSM (all p < 0.001), whereas administration of Huaier was identified as a protective factor (HR = 0.32, 95% CI: 0.24–0.41; p < 0.001). This evidence concerns the gene GPT and neoplasm.