In colon tumor tissues, the overexpression of PPARβ/δ intensified the activation of the adhesion protein β-catenin and several factors involved in cancer cell invasion, such as connexin 43, platelet-derived growth factor receptor β (PDGFRβ), Akt1, EIF4G1, and CDK1, all of which promote colorectal cancer progression (Liu et al., 2019a). Here, PPARD is linked to cancer.