Culture of MCF0742 (breast cancer) and UACC501516 (melanoma) cells in the presence of GW0742 caused upregulation of the PPARβ/δ target gene angiopoietin-like protein 4 (ANGPTL4), and the growth of both tumor cell lines was inhibited (Girroir et al., 2008). The gene discussed is ANGPTL4; the disease is melanoma.