HK2 and gastric cancer: 5) In gastric cancer, fenofibrate induces mitochondrial body mass programming through CPT1 and fatty acid oxidation pathways, as well as activating the AMPK pathway and inhibiting the HK2 pathway, thereby regulating glycolipid metabolism, inhibiting the growth of gastric cancer cells, and causing apoptosis of gastric cancer cells (Chen et al., 2020).