RIPK3 and myocardial ischemia: Sevoflurane postconditioning-induced enhancement of O-GlcNAcylation of RIPK3 (necrosis regulatory protein) inhibits myocardial ischemia-reperfusion injury-mediated necrosis through inhibition of RIPK3/MLKL (a key mediator of necrosis) complex formation (Zhang et al., 2020).