To investigate the function of the TLR4-IRF3-IFNβ-STAT1α/β axis on venous thrombosis resolution, we evaluated IFNβ and MCP-5 expression by ELISA in Tlr4−/− and WT mice at 1, 3, and 7 subsequent days after IVC ligation. This evidence concerns the gene IRF3 and Venous thrombosis.