PLAU and deep vein thrombosis: To study the involvement of the TLR4/NF-κB signalling in DVT resolution in vitro, we detected IκBα phosphorylation, p65 nuclear translocation and transcription of MCP-1, MMP-9 and urokinase plasminogen activator (uPA) in peritoneal macrophages from TLR4-intact and TLR4-deficient mice.