MALAT1 and chronic obstructive pulmonary disease: The ROC curve analysis revealed that MALAT1 expression discriminates from acute exacerbation COPD patients from the healthy subjects (sensitivity and specificity 99.2% and 83.3%, respectively) and the stable COPD patients (64.2% and 83.3%, respectively), indicating that MALAT1 could be used as a biomarker in COPD.