A previous study by Hu et al., measured expression levels of six selected lncRNAs based on their involvement in different lung diseases (HOTAIR, HULC, MEG3, NEAT1, UCA1, and MALAT1) by RT-qPCR in the lung tissues collected from three pairs of age-matched COPD and non-COPD individuals (Hu et al., 2020). This evidence concerns the gene HOTAIR and chronic obstructive pulmonary disease.