CD4 and lymphedema: IL-17A production in CD4+, CD4+PD-1+, and CD4+PD-1- cells was downregulated in post-LVA compared to that in lymphedema (2.7 [1.8–3.3] vs. 1.6 [0.9–2.3], p = 0.01; 5.5 [3.6–6.3] vs. 4.0 [2.7–4.5], p = 0.04; and 1.3 [0.8–2.5] vs. 0.8 [0.4–1.6], p = 0.01, respectively) (Figures 7G–7I).