The reference range i.e., 129-216 U/ mL, indicates the development of microvascular damage, which is supported by the study of Fei et al.19 However, this is not supported by the local study done in Rawalpindi, Karachi by Huma et al.20 On correlating the PFT parameters with SOD in patients suffering from T1D and T2D, no significant result was shown (Tables II and III). Here, SOD1 is linked to type 1 diabetes mellitus.