The applications of tau PET in differentiating AD-D from other neurodegenerative cognitive disorders such as frontotemporal dementia (FTD) and dementia with Lewy bodies (DLB) have been explored before (Gomperts et al., 2016; Ossenkoppele et al., 2018; Kroth et al., 2019; Tsai et al., 2019; Mak et al., 2021). The gene discussed is MAPT; the disease is frontotemporal dementia.