When the serological test results used in the diagnosis of CD were examined in our study, gliadin IgA and IgG positivities were found in 33.7% (n = 54/160) and 39.4% (n = 69/175); endomysium IgA and IgG positivities were found in 37% (n = 88/238) and 18% (n = 30/167); tissue transglutaminase IgA and IgG positivities were found in 47.3% (n = 115/243) and 16.3% (n = 15/92). Here, TGM2 is linked to Cowden disease.