In this study, we screened 11 important lncRNAs (AFAP1-AS1, MIR155HG, LINC00472, and FAM201A) and mRNAs (CASP10, SLC26A2, TRIB1, BMP2K, SCAMP1, TNKS1BP1, and MBOAT2) according to the gene expression profiles of gastric epithelial tissues in different stages of Hp infection-induced gastritis. This evidence concerns the gene AFAP1 and gastritis.