GAS5 and gastric cancer: The overexpression of HOTATR promoted the proliferation and migration of GC cells, and the knockdown of HOTATR expression significantly inhibited tumor proliferation.45 The expression level of CCATI in GC tissues is significantly higher than that in healthy tissues, and its overexpression can promote the proliferation and invasion of tumor cells.46 GAS5 is an lncRNA with tumor-suppressing function, and its expression level is significantly downregulated in various tumors, such as breast and pancreatic cancers.