INS and type 1 diabetes mellitus: Higher basal and stimulated C-peptide levels (36,37), younger age and higher BMI at diagnosis (38), higher insulin sensitivity (39), male sex (40–42), lower initial HbA1c level at diagnosis (40,42,43), age at T1D onset ≥ 5 years (42–45), initial islet autoantibody negativity (42), and disease onset without DKA (42) have been associated with a higher likelihood of experiencing the remission phase across different studies conducted on patients with T1D.