However, intra-abdominal fat deposition is positively correlated with insulin levels and hyperandrogenism in PCOS (18) i.e., hyperandrogenism, independent of BMI and HOMA in women with PCOS, is associated with preferential deposition of fat in the abdominal region, linking visceral fat, hyperinsulinemia, and hyperandrogenism. The gene discussed is INS; the disease is Hyperinsulinemia.