Neurensin‐2 (NRSN2) also promotes breast cancer metastasis by activating the PI3K/AKT/mTOR and NF‐κB signaling pathways,46 and melittin suppresses EGF‐induced cell motility and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway in breast cancer cells.47 This evidence concerns the gene NFKB1 and breast cancer.