Combining the analysis results of The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) databases revealed that VPS4A/4B/8/11/13A/13B/13C/13D/16/18/25/26A/26B/28/29/33A/33B/35/37A/37C/37D/39/41/45/52/53/54/72 was significantly overexpressed in HCC tissues more than in normal liver tissues (Figure 1A,B). The gene discussed is VPS4A; the disease is hepatocellular carcinoma.