As summarized in the WHO CNS5, the mutation-site genotypes of genes such as isocitrate dehydrogenase (IDH), tumor protein p53 (P53), and alpha thalassemia/mental retardation syndrome X-linked (ATRX) are important indicators for the classification of gliomas [13]. This evidence concerns the gene TP53 and alpha thalassemia-X-linked intellectual disability syndrome.