A GSEA analysis using gProfiler [41] of all IGF2BP2 targets that are differentially expressed and showing a log2 fold change > 0.5 in tumor versus normal and/or metastastatic versus normal liver tissues revealed an enrichment being most significant for Gene Ontology (GO) biological processes and REACTOME pathways linked to cell cycle (Supplementary tables S3, S4 and S5). This evidence concerns the gene IGF2BP2 and neoplasm.