The gene CBS had a certain inhibitory effect on the occurrence of HCC (Fig. 3G), while the other seven genes (TOP2A, BIRC5, VEGFA, HIF1A, FTH1, ACSL3, SLC7A11) had a certain promoting effect on the occurrence of HCC (Fig. 3E–L). Here, HIF1A is linked to hepatocellular carcinoma.