Among damaging missense mDNVs, the missense mDNV in SLC35A2 was of particular interest because several mDNVs in SLC35A2 are causal for malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE), an epileptic syndrome with neuropathological abnormality in the brain [58], while gDNVs in SLC35A2 are causal for a developmental disorder, congenital disorders of glycosylation (CDG) [59] (Fig. 3A). This evidence concerns the gene SLC35A2 and epilepsy syndrome.