We analyzed 15 hub genes (SNRPA, NCBP2, EIF2S2, NOP58, PES1, PA2G4, RAN, UBE2S, PHC2, EZH2, KIFC1, CDC20, KIF2C, E2F2, and PLK1) coexpressed with BAIAP2L2 in HCC to investigate the potential function of BAIAP2L2 in HCC. The gene discussed is E2F2; the disease is hepatocellular carcinoma.