Grossly and histologically, we did not find gastric lesions in Atp4b-cre/T antigen and Capn8-cre/T antigen mice (data not shown), but we found a poorly differentiated carcinoma in K19-cre/T antigen (37.5%, 3/8) mice at 16–19 months of age according to HE staining (Table 2). This evidence concerns the gene CAPN8 and carcinoma.