With regard to endocrine-specific genes, COVID-19 cases were characterized by suppressed levels of hormonal transcripts in both virus-positive and virus-negative cases compared to controls (insulin (INS) FC = −1.22, FDR = 0.22 and FC = −1.47, FDR = 0.17 respectively; islet amyloid polypeptide (IAPP) FC = −2.07, FDR = 0.11 in virus-positive and FC = −1.67, FDR = 0.21 in virus-negative cases). The gene discussed is IAPP; the disease is COVID-19.