The proliferation ability of GBM (U251 and LN229) cells treated with RARRES2 siRNA was detected by EdU assay, and we found that RARRES2 siRNA treatment decreased the green fluorescence intensity, suggesting that the proliferation ability of GBM cells was inhibited by siRARRES2 (Fig. 8A–B). The gene discussed is RARRES2; the disease is glioblastoma.