IL33 and inborn error of immunity: In a gene set enrichment analysis (GSEA), the gene sets of proteasome [58] and glycolysis/gluconeogenesis [59, 60] related to the activation or cross-priming of DCs were positively enriched in the IL-33-induced CD103+ cDC1s compared with the GM-CSF-induced CD103+ cDC1s, whereas the gene set of primary immunodeficiency was negatively enriched in the IL-33-induced CD103+ cDC1s (Fig. 4B).