PKM and diabetes mellitus: The most important Minar2-interacting proteins linked to diabetes, metabolism, and body mass index are shown in Figure 5A. The top Minar2-interacting proteins with a link to metabolism were FN3K, raptor, PFKL, ACYL, PLS3, PKM, PFKB, PIP5K2C, and CDK1 (Figure 5A).