FZD4 and familial pancreatic carcinoma: A similar study found that the zinc finger E-box-binding protein DLX6-AS1, upon interacting with miR-181b, promoted cell proliferation, migration, metastasis, and inhibition of apoptosis in pancreatic cancer via up-regulation of the Wnt/beta-catenin signaling pathway and the FZD4/FZD6 signaling pathway (ZEB2).