Several factors may contribute to implant failure: soft tissue defects for tumor cases and poor soft tissue condition in revision cases leading to instability [3, 4] bone quality and cement technique that may contribute to loosening and prosthetic or peri-prosthetic fracture [3]; chemotherapy and radiotherapy, large bone defects and prostheses, increasing surgery time (> 2.5 h), increased patient body mass index, lower preoperative hemoglobin or albumin levels, and postoperative hematoma contribute to a higher risk of infection [3, 5]. This evidence concerns the gene ALB and neoplasm.