Lastly, we also reported a cluster of zinc finger proteins (ZNF350, ZNF331, ZNF160, ZNF83) located on 19q13.41, which belong to a Krüppel-type family of transcriptional repressors, and have previously been shown to be epigenetically silenced and downregulated in multiple cancers [66, 67] including head and neck cancers [68]. This evidence concerns the gene ZNF331 and head and neck cancer.