An online KM plotter database (http://kmplot.com/analysis/) using microarray data showed that Lnc-MALAT1 and TOP2A expression was significantly correlated with OS (overall survival) in 1880 breast cancer patients (HR = 1.56, P = 0.0014, and HR = 2, P = 3.5 e−10, respectively) (Fig. 1F,G). The gene discussed is TOP2A; the disease is breast cancer.