In vivo, D-carnosine octyl ester alleviates atherosclerosis in ApoE-/- mice by decreasing general serum carbonylated protein levels.494 Oolong tea derived-oolonghomobisflavan A (OFA) prevents atherosclerosis by reducing oxidative stress and carbonylation of ApoB100.156. This evidence concerns the gene APOB and atherosclerosis.