IFNG and neoplasm: Notably, genes involved in the “HALLMARK_TGF_BETA_SIGNALING” (genes up-regulated in response to the ligand of the TGF-beta superfamily of proteins) and “HALLMARK_INTERFERON_GAMMA_RESPONSE” (genes up-regulated in response to Interferon-gamma) were also highly positively enriched in samples of tumor thrombus (Fig. 1C).