Anti-IFN aAbs were initially found in patients treated with IFN-α or IFN-β [88], before being found in patients with chronic graft-versus-host disease following allogeneic bone marrow transplantation [89], myasthenia gravis [90], or thymoma [91] as well as in some women with SLE [43]. The gene discussed is IFNA1; the disease is systemic lupus erythematosus.