DOCK11 and hepatocellular carcinoma: In addition, through single-cell transcriptome analysis using a newly established cell line called KM, which maintains long-term HBV infection, originating from a HCC patient, and xenotransplanted into NOD/SCID mice, in which we could detect cccDNA and HBV DNA, as well as HBV-derived transcripts, we recently identified the dedicator of cytokinesis 11 (DOCK11), which regulates cytokinesis by acting through guanine exchange factor (GEF) activity as a host factor associated with HBV maintenance [10].