Interestingly, the authors measured DROSHA, DGCR8, XPO5, DICER1, AGO2, and AGO3 mRNA expression, and only DICER1 mRNA was differently expressed in CD8+ T-cell–depleted PBMCs from HTLV-1 asymptomatic carriers when compared to patients with acute adult T cell Leukemia. The gene discussed is AGO3; the disease is adult T-cell leukemia/lymphoma.